KDM4A Antibody

APR08085G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR08085G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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KDM4A Antibody

品牌	Leading Biology	貨號	APR08085G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KDM4A antibody.
分子量	120kDa
細胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00537, ECO:0000269\|PubMed:15927959, ECO:0000269\|PubMed:16024779}
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	5H1
亞型	IgG1
通用名	JHDM3A, JMJD2, JMJD2A, KIAA0677
基因ID	9682
UniProt ID	O75164
功能	Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, ICC, E
稀釋方法	WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000
別名	Lysine-specific demethylase 4A, 1.14.11.-, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, KDM4A, JHDM3A, JMJD2, JMJD2A, KIAA0677
圖像	Figure 1: Western blot analysis using KDM4A mAb against HEK293 (1) and KDM4A(AA: 500-705)-hIgGFc transfected HEK293 (2) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining. Figure 3: Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
說明書	Product Datasheet Protocol
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