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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > ENC1 Antibody (monoclonal) (M02)

ENC1 Antibody (monoclonal) (M02)

貨號 貨期 規(guī)格 / 價格 詢價
APR11825G 100 μg / ¥4950

ENC1 Antibody (monoclonal) (M02)

品牌

Leading Biology

貨號

APR11825G

產(chǎn)品分類

Monoclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ENC1 antibody (monoclonal) (M02).

分子量

66130 Da

宿主

mouse

種屬反應性

Human

靶點

ENC1 (NP_003624, 17 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆號

3B1

亞型

IgG1 Kappa

基因ID

UniProt ID

總結(jié)

DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) [PubMed 9305847] used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) [PubMed 9305847] termed these genes 'p53-induced genes,' or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.

形式

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, E

稀釋方法

WB~~1:500~1000

別名

Ectoderm-neural cortex protein 1, ENC-1, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced gene 10 protein, ENC1, KLHL37, NRPB, PIG10

圖像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.76 KDa) .

ENC1 monoclonal antibody (M02), clone 3B1 Western Blot analysis of ENC1 expression in IMR-32 ( (Cat APR11825G )

Detection limit for recombinant GST tagged ENC1 is approximately 0.3ng/ml as a capture antibody.

說明書

數(shù)量

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