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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > DUSP6 Antibody (monoclonal) (M01)

DUSP6 Antibody (monoclonal) (M01)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG03249G 100 μg / ¥4950

DUSP6 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號(hào)

APG03249G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DUSP6 antibody (monoclonal) (M01).

分子量

42320 Da

宿主

mouse

種屬反應(yīng)性

Human

靶點(diǎn)

DUSP6 (AAH03143, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆號(hào)

3G2

亞型

IgG1 Kappa

基因ID

UniProt ID

總結(jié)

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

形式

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC, IF, E

稀釋方法

WB~~1:500~1000

別名

Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3, DUSP6, MKP3, PYST1

圖像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (67.65 KDa) .

Western Blot analysis of DUSP6 expression in transfected 293T cell line by DUSP6 monoclonal antibody (M01), clone 3G2. Lane 1: DUSP6 transfected lysate(42 KDa). Lane 2: Non-transfected lysate.

Immunoperoxidase of monoclonal antibody to DUSP6 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]

說明書

數(shù)量

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