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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
AMM06973G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DUSP5 antibody (monoclonal) (M04).
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分子量 |
42047 Da
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宿主 |
mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
DUSP5 (NP_004410, 286 a.a. ~ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號(hào) |
2F3
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亞型 |
IgG2b Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, E
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稀釋方法 |
WB~~1:500~1000
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別名 |
Dual specificity protein phosphatase 5, Dual specificity protein phosphatase hVH3, DUSP5, VH3
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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