全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR15372G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CDC42EP2 antibody (monoclonal) (M01).
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分子量 |
22484 Da
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宿主 |
mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
CDC42EP2 (NP_006770, 102 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號(hào) |
2H7
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亞型 |
IgG1 Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:500~1000
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別名 |
Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
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圖像 |
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說明書 |
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數(shù)量 |
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