Neurofilament M (NF-M) Antibody

AMM06638G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM06638G		100 μl / ￥4950

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Neurofilament M (NF-M) Antibody

品牌	Leading Biology	貨號	AMM06638G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neurofilament M (NF-M) antibody.
分子量	145 KDa
宿主	Mouse
種屬反應(yīng)性	Rat
靶點	Preparation containing the extreme C-terminus expressed in and purified from E. Coli.
克隆號	3H11
亞型	IgG1
基因ID	24588
UniProt ID	P12839
總結(jié)	Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2).
形式	Unpurified, concentrated culture supernatant.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IF, WB
稀釋方法	WB~~ 1:1000 IF~~ 1:100
別名	Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, Nefm, Nef3, Nfm
圖像	Western blot of rat cortex lysate showing specific immunolabeling of the ~ 145k NF-M protein. Immunostaining of cultured rat neurons showing labeling of NF-M (green) in mature neurons.
說明書	Product Datasheet Protocol
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