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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > UGT1A9 (Hepatocyte & Hepatocellular Carcinoma Marker) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
APG01365G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UGT1A9 (Hepatocyte & Hepatocellular Carcinoma Marker) antibody - Without BSA and Azide.
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分子量 |
~60kDa
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細胞定位 |
Antigen Cellular Localization:
Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
UGT1A9/1229
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亞型 |
Mouse / IgG2b, kappa
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通用名 |
GNT1, UGT1
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基因ID |
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UniProt ID |
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功能 |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
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總結(jié) |
It recognizes a protein of about 60kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IF, FC
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別名 |
UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, 2.4.1.17, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, UDP-glucuronosyltransferase 1A9, lugP4, UGT1A9, GNT1, UGT1
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說明書 |
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數(shù)量 |
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