Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide

APR14516G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14516G		100 μg / ￥4950

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Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide

品牌	Leading Biology	貨號	APR14516G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytokeratin 18 (KRT18) antibody - Without BSA and Azide.
分子量	45kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, perinuclear region. Nucleus, nucleolus
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	DA7
亞型	Mouse / IgG1, kappa
通用名	CYK18
基因ID	3875
UniProt ID	P05783
功能	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
總結(jié)	This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
形式	200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, FC
別名	Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
圖像	Western Blot of HeLa Cell Lysate using Cytokeratin 18 Monoclonal Antibody (DA7). Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Cytokeratin 18 Monoclonal Antibody (DA7).
說明書	Product Datasheet Protocol
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Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide