PARL Antibody

APR08926G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR08926G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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PARL Antibody

品牌	Leading Biology	貨號(hào)	APR08926G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PARL antibody.
分子量	42190 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	8C4B2; 1H12E10
亞型	IgG2b
通用名	PSARL
基因ID	55486
UniProt ID	Q9H300
功能	Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1/500 - 1/2000 IHC~~1:200~~1000 IF~~1:200~1000.
別名	Presenilins-associated rhomboid-like protein, mitochondrial, 3.4.21.105, Mitochondrial intramembrane cleaving protease PARL, P-beta, Pbeta, PARL, PSARL
圖像	Figure 1: Western blot analysis using PARL mouse mAb against truncated Trx-PARL recombinant protein (1) and truncated MBP-PARL(aa112-167) recombinant protein (2). Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebra (left) and lung carcinoma (right) tissues, showing nuclear localization with DAB staining using MDM4 mouse mAb. Figure 3: Confocal immunofluorescence analysis of Hela (left) and L-02 (right) cells using anti-MDM4 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin.
說(shuō)明書	Product Datasheet Protocol
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