品牌 |
Leading Biology | 貨號(hào) |
APG02420G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Caspase-9 antibody.
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分子量 |
49,37 KDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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通用名 |
MCH6
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基因ID |
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UniProt ID |
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功能 |
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).
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總結(jié) |
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).
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形式 |
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide,and 50% glycerol.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:1000
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別名 |
APAF 3;APAF-3;APAF3;Apoptosis related cysteine peptidase;Apoptotic protease activating factor 3;Apoptotic protease Mch 6;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;CASP 9;CASP-9;CASP9;CASP9_HUMAN;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9;Caspase-9 subunit p10;Caspase9;ICE LAP6;ICE like apoptotic protease 6;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1, regulatory subunit 56;RNCASP9
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圖像 |
Western blot detection of Caspase-9 in A549,MCF7,Jurkat,K562 and Hela cell lysates using Caspase-9 mouse mAb (1:1000 diluted).Predicted band size:49/37KDa.Observed band size:49KDa. |
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說(shuō)明書(shū) |
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數(shù)量 |
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