全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06264G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LGALS3 antibody (C-term) (ascites).
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分子量 |
26152 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
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宿主 |
Mouse
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種屬反應性 |
Human
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免疫原 |
163-191 aa
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靶點 |
This LGALS3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human LGALS3.
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克隆號 |
320CT4.5.2
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亞型 |
IgG1
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通用名 |
MAC2
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基因ID |
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UniProt ID |
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功能 |
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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總結 |
This gene encodes a member of the galectin family ofcarbohydrate binding proteins. Members of this protein family havean affinity for beta-galactosides. The encoded protein ischaracterized by an N-terminal proline-rich tandem repeat domainand a single C-terminal carbohydrate recognition domain. Thisprotein can self-associate through the N-terminal domain allowingit to bind to multivalent saccharide ligands. This proteinlocalizes to the extracellular matrix, the cytoplasm and thenucleus. This protein plays a role in numerous cellular functionsincluding apoptosis, innate immunity, cell adhesion and T-cellregulation. Alternate splicing results in multiple transcriptvariants.
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:500~4000
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別名 |
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
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圖像 |
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說明書 |
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數(shù)量 |
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