品牌 |
Leading Biology | 貨號 |
APG02479G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD138 antibody (C-term) (Ascites).
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分子量 |
32462 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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免疫原 |
210-238 aa
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靶點 |
This CD138 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.
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克隆號 |
587CT7.3.6.5
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亞型 |
IgM
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通用名 |
SDC
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基因ID |
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UniProt ID |
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功能 |
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
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總結(jié) |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, IF, E
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稀釋方法 |
WB~~1:500~8000
FC~~1:10~50
IF~~1:10~50
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別名 |
Syndecan-1, SYND1, CD138, SDC1, SDC
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圖像 |
CD138 Antibody (C-term)(Ascites)(Cat. APG02479G) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the CD138 antibody detected the CD138 protein (arrow). CD138 Antibody (C-term) (Ascites) (Cat. APG02479G) flow cytometric analysis of U266 cells (right histogram) compared to a negative control cell (left histogram).Alexa Fluor? 488-conjugated donkey anti-mouse lgG secondary antibodies were used for the analysis CD138 Antibody (C-term) (Ascites) (Cat. APG02479G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).Alexa Fluor? 488-conjugated donkey anti-mouse lgG secondary antibodies were used for the analysis |
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說明書 |
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數(shù)量 |
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