全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR11965G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GABARAP antibody.
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分子量 |
13918 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity)
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
Purified His-tagged GABARAP protein(Fragment) was used to produced this monoclonal antibody.
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克隆號(hào) |
424CT5.1.6
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亞型 |
IgG1
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通用名 |
FLC3B
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基因ID |
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UniProt ID |
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功能 |
Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
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總結(jié) |
Gamma-aminobutyric acid A receptors [GABA(A) receptors]are ligand-gated chloride channels that mediate inhibitoryneurotransmission. This gene encodes GABA(A) receptor-associatedprotein, which is highly positively charged in its N-terminus andshares sequence similarity with light chain-3 ofmicrotubule-associated proteins 1A and 1B. This protein clustersneurotransmitter receptors by mediating interaction with thecytoskeleton.
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形式 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:100~250
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別名 |
Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein, MM46, GABARAP, FLC3B
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圖像 |
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說明書 |
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數(shù)量 |
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