全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR12378G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HNMT antibody.
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分子量 |
33295 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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種屬反應性 |
Human
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靶點 |
Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.
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克隆號 |
432CT31.4.2
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
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總結(jié) |
In mammals, histamine is metabolized by two majorpathways: N(tau)-methylation via histamine N-methyltransferase andoxidative deamination via diamine oxidase. This gene encodes thefirst enzyme which is found in the cytosol and usesS-adenosyl-L-methionine as the methyl donor. In the mammalianbrain, the neurotransmitter activity of histamine is controlled byN(tau)-methylation as diamine oxidase is not found in the centralnervous system. A common genetic polymorphism affects the activitylevels of this gene product in red blood cells. Multiplealternatively spliced transcript variants that encode differentproteins have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:100~1000
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別名 |
Histamine N-methyltransferase, HMT, HNMT
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圖像 |
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說明書 |
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數(shù)量 |
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