HNMT Antibody(Ascites)

APR12380G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12380G		0.1 ml / ￥4950

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HNMT Antibody(Ascites)

品牌	Leading Biology	貨號(hào)	APR12380G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNMT antibody(Ascites).
分子量	33295 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Mouse
種屬反應(yīng)性	Human
靶點(diǎn)	Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.
克隆號(hào)	432CT31.4.2
亞型	IgG1
基因ID	3176
UniProt ID	P50135
功能	Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
總結(jié)	In mammals, histamine is metabolized by two majorpathways: N(tau)-methylation via histamine N-methyltransferase andoxidative deamination via diamine oxidase. This gene encodes thefirst enzyme which is found in the cytosol and usesS-adenosyl-L-methionine as the methyl donor. In the mammalianbrain, the neurotransmitter activity of histamine is controlled byN(tau)-methylation as diamine oxidase is not found in the centralnervous system. A common genetic polymorphism affects the activitylevels of this gene product in red blood cells. Multiplealternatively spliced transcript variants that encode differentproteins have been found for this gene.
形式	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:100~8000
別名	Histamine N-methyltransferase, HMT, HNMT
圖像	HNMT Antibody (Cat. APR12380G) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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