TLE1 Antibody (Center)

AMM08211G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM08211G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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TLE1 Antibody (Center)

品牌	Leading Biology	貨號	AMM08211G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLE1 antibody (Center).
分子量	83201 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Note=Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	199-228 aa
靶點	This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.
克隆號	381CT18.5.1
亞型	IgG1
基因ID	7088
UniProt ID	Q04724
功能	Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
總結(jié)	Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
形式	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:100~250
別名	Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1, ESG1, TLE1
圖像	TLE1 Antibody (Center) (Cat. AMM08211G) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the TLE1 antibody detected the TLE1 protein (arrow).
說明書	Product Datasheet Protocol
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