全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM08212G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TLE1 antibody (Center) (Ascites).
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分子量 |
83201 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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免疫原 |
199-228 aa
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靶點(diǎn) |
This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.
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克隆號(hào) |
381CT18.5.1
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
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總結(jié) |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:500~8000
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別名 |
Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1, ESG1, TLE1
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圖像 |
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說明書 |
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數(shù)量 |
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