LGALS3 Antibody (C-term)

AMM06263G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06263G		100 μl / ￥4950

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LGALS3 Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMM06263G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LGALS3 antibody (C-term).
分子量	26152 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	163-191 aa
靶點(diǎn)	This LGALS3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human LGALS3.
克隆號(hào)	320CT4.5.2
亞型	IgG1,k
通用名	MAC2
基因ID	3958
UniProt ID	P17931
功能	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
總結(jié)	This gene encodes a member of the galectin family ofcarbohydrate binding proteins. Members of this protein family havean affinity for beta-galactosides. The encoded protein ischaracterized by an N-terminal proline-rich tandem repeat domainand a single C-terminal carbohydrate recognition domain. Thisprotein can self-associate through the N-terminal domain allowingit to bind to multivalent saccharide ligands. This proteinlocalizes to the extracellular matrix, the cytoplasm and thenucleus. This protein plays a role in numerous cellular functionsincluding apoptosis, innate immunity, cell adhesion and T-cellregulation. Alternate splicing results in multiple transcriptvariants.
形式	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:100~500 IHC-P~~1:10~50
別名	Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
圖像	LGALS3 Antibody (C-term) (Cat. AMM06263G) western blot analysis in NCI-H460 cell line lysates (35μg/lane).This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow). LGALS3 Antibody (C-term) (Cat. AMM06263G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjμgation of the secondary antibody and DAB staining.This data demonstrates the use of LGALS3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. LGALS3 Antibody (C-term) (Cat. AMM06263G)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjμgation of the secondary antibody and DAB staining.This data demonstrates the use of LGALS3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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