Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody - With BSA and Azide

APR14608G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14608G		50 μg / ￥3950

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Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody - With BSA and Azide

品牌	Leading Biology	貨號	APR14608G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) antibody - With BSA and Azide.
分子量	67kDa (CK1); 58kDa (CK5); 56.5kDa (CK10); 50kDa (CK14)
細胞定位	Antigen Cellular Localization: Cell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cells
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Rat
靶點	Solubilized keratin extract from human stratum corneum
克隆號	34BE12
亞型	IgG1, kappa
通用名	KRTA
基因ID	3848
UniProt ID	P04264
功能	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
總結(jié)	This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.
形式	0.5 ml at 200ug/ml with BSA and azide
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, FC, IP
別名	Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA
圖像	Formalin-fixed, paraffin-embedded human prostate (10X) stained with Cytokeratin, HMW MAb (34bE12). Formalin-fixed, paraffin-embedded human prostate (20X) stained with Cytokeratin, HMW MAb (34bE12).
說明書	Product Datasheet Protocol
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Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody - With BSA and Azide