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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > AMACR / p504S (Prostate Cancer Marker) Antibody - Culture Supernatant品牌 |
Leading Biology | 貨號(hào) |
APR07207G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMACR / p504S (Prostate Cancer Marker) antibody - Culture Supernatant .
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分子量 |
54kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Peroxisome. Mitochondrion
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Full length human recombinant AMACR protein
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克隆號(hào) |
13H4
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.
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總結(jié) |
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
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形式 |
0.5 ml of Culture Supernatant with azide
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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別名 |
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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