品牌 |
Leading Biology | 貨號 |
APR10934G |
產品分類 |
Monoclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality THBS1 antibody (Center).
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分子量 |
129383 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum. Sarcoplasmic reticulum
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宿主 |
Mouse
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種屬反應性 |
Human
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免疫原 |
763-789 aa
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靶點 |
This THBS1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 763-789 amino acids from the Central region of human THBS1.
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克隆號 |
518CT18.12.8
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亞型 |
IgM
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通用名 |
TSP, TSP1
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基因ID |
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UniProt ID |
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功能 |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
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總結 |
The protein encoded by this gene is a subunit of adisulfide-linked homotrimeric protein. This protein is an adhesiveglycoprotein that mediates cell-to-cell and cell-to-matrixinteractions. This protein can bind to fibrinogen, fibronectin,laminin, type V collagen and integrins alpha-V/beta-1. This proteinhas been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.
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形式 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:100~250
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別名 |
Thrombospondin-1, THBS1, TSP, TSP1
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圖像 |
THBS1 Antibody (Center)(Cat. APR10934G) western blot analysis in MDA-MB231 cell line lysates (35μg/lane).This demonstrates the THBS1 antibody detected the THBS1 protein (arrow). |
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說明書 |
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數(shù)量 |
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