TFF1 Antibody

AMM08170G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
AMM08170G		100 μl / ￥5450

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TFF1 Antibody

品牌	Leading Biology	貨號(hào)	AMM08170G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TFF1 antibody.
分子量	9150 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	A synthetic peptide corresponding to residues in human TFF1 was used as an immunogen.
克隆號(hào)	EPR3972
通用名	BCEI, PS2
基因ID	7031
UniProt ID	P04155
功能	Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
總結(jié)	Trefoil factor 1 (TFF1), a member of the trefoil factor family, is a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents (1). It belongs to a family of abundant GI3 peptides with a distinct 3-loop structure formed by a highly conserved motif of cysteine disulfide bonds, which confer them with luminal stability (2). TFF peptides, closely associated with mucins, are mainly synthesized and secreted by mucin-secreting epithelial cells lining the gastrointestinal tract (3). It is specifically found in the stomach, with highest expression levels in the upper gastric mucosal cells (1). TFF1 is most strongly expressed in pancreas, large bowel, and breast cancer (1). In breast cancer, its regulation by estrogen is an indicator of estrogen receptor (ER) functionality (4).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:1000~10000 IHC~~1:100~250
別名	Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1A, hP1A, Protein pS2, TFF1, BCEI, PS2
圖像	Western blot analysis on (A) human stomach and (B) MCF-7 cell lysates using anti-TFF1 RabMAb (Cat. AMM08170G). Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-TFF1 RabMAb (Cat. AMM08170G). Immunohistochemical analysis of paraffin-embedded human stomach tissue using anti-TFF1 RabMAb (Cat. AMM08170G).
說(shuō)明書(shū)	Product Datasheet Protocol
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