Synapsin II Antibody

APR13612G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR13612G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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Synapsin II Antibody

品牌	Leading Biology	貨號(hào)	APR13612G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Synapsin II antibody.
分子量	62847 Da
細(xì)胞定位	Antigen Cellular Localization: Cell junction, synapse.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in human Synapsin II was used as an immunogen.
克隆號(hào)	EPR3277
基因ID	6854
UniProt ID	Q92777
功能	Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons (By similarity).
總結(jié)	The synapsins are a family of at least five proteins that are specifically associated with the cytoplasmic surface of synaptic vesicles (1, 2). They are neuron-specific phosphoproteins that selectively bind to small synaptic vesicles in the presynaptic nerve terminal (3). The synapsins are implicated in neurotransmitter release and synaptogenesis, processes believed to be aberrant in several neuropsychiatric diseases (1). Synapsin II has been reported to specifically be involved in the formation and maintenance of synapses in hippocampal neurons (4). It has also been found to play a distinct role in neuronal development, as a study reported that the deletion of synapsin II greatly retarded axon formation, and the deletion of synapsin I retarded synapse formation (5). Synapsin II was furthermore suggested to participate in cytoskeletal organization during the early stages of nerve cell development (6).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:5000~10000 IHC~~1:100~250
別名	Synapsin-2, Synapsin II, SYN2
圖像	A.Western blot analysis on fetal brain cell lysate using anti-Synapsin II RabMAb (Cat. APR13612G), dilution 1:20,000. B. Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-SynapsinII RabMAb (Cat. APR13612G). C. Immunofluorescent staining of Sh-SY-5Y cells using anti-SynapsinII RabMAb (Cat. APR13612G).
說明書	Product Datasheet Protocol
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