p16-Arc Antibody (N-term)

APR17707G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR17707G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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p16-Arc Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR17707G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality p16-Arc antibody (N-term).
分子量	16320 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cell projection
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues on the N-terminus of human p16-ARC was used as an immunogen.
克隆號(hào)	EP1551Y
通用名	ARC16
基因ID	10092
UniProt ID	O15511
功能	Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
總結(jié)	The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc (p complex) (1). These proteins localize in the cytoplasm of fibroblasts that lack lamellipodia, but are enriched in lamellipodia on stimulation with serum or platelet-derived growth factor. A dynamic role for this complex in the organization of the actin cytoskeleton has been suggested (2). p16-Arc has been found to be a globular alpha-helical subunit (3).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:1000~10000 IHC~~1:50~100
別名	Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5, ARC16
圖像	A. Western blot analysis on fetal brain lysate using anti-p16 Arc RabMAb (Cat. APR17707G), dilution 1:20,000 B. Immunohistochemical analysis of paraffin-embedded human uterus adenocarcinoma using anti-p16-ARC RabMAb (Cat. APR17707G).
說明書	Product Datasheet Protocol
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