Calmodulin Antibody (CaM) (C-term)

APR07083G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR07083G		100 μl / ￥5450

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Calmodulin Antibody (CaM) (C-term)

品牌	Leading Biology	貨號(hào)	APR07083G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Calmodulin antibody (CaM) (C-term).
分子量	16838 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in the C-terminus of human Calmodulin was used as immunogen.
克隆號(hào)	EP799Y
通用名	CALM, CAM, CAM1
基因ID	801;805;808
UniProt ID	P62158
功能	Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
總結(jié)	Calmoduin (CaM) is a calcium modulator protein and a transducer of calcium signals (1-2). Upon calcium binding, calmodulin undergoes conformational changes and binds and modulates a diverse array of proteins. Calcium-bound CaM (Ca2+-CaM) can assume a variety of shapes depending on the target (3). Ca2+-CaM binds many kinases, phosphatases, signaling proteins, and structural proteins affecting a wide variety of processes including neurotransmitter release, muscle contraction, metabolism, apoptosis, inflammation, membrane protein organization, and cytoskeleton movement (2, 4-5).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:1000~2000 IHC~~1:250~500
別名	Calmodulin, CaM, CALM1, CALM, CAM, CAM1
圖像	A. Western blot analysis on NIH 3T3 cell lysate using anti-Calmodulin (C-term) RabMAb (Cat. APR07083G), dilution 1:5,000 B. Immunohistochemical analysis of paraffin-embedded human urinary bladder carcinoma using anti-Calmodulin RabMAb (Cat. APR07083G).
說明書	Product Datasheet Protocol
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