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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Retinoid X Receptor, β-Isotype Antibody

Retinoid X Receptor, β-Isotype Antibody

貨號 貨期 規(guī)格 / 價格 詢價
AMM02583G 100 μl / ¥5450

Retinoid X Receptor, β-Isotype Antibody

品牌

Leading Biology

貨號

AMM02583G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Retinoid X Receptor, β-Isotype Antibody.

分子量

48 KDa

宿主

Mouse

種屬反應(yīng)性

Mouse, Rat

靶點

Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH.

克隆號

147

亞型

IgG1

基因ID

UniProt ID

總結(jié)

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB

稀釋方法

WB~~ 1:1000

圖像

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~48k RXR-β protein.

說明書

數(shù)量

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