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當(dāng)前位置：首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD33 Antibody

CD33 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM02683G 100 μl / ￥5450

CD33 Antibody

品牌

 Leading Biology

貨號(hào)

 AMM02683G

產(chǎn)品分類

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD33 Antibody.

分子量
39825 Da

細(xì)胞定位
Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

宿主
Mouse

種屬反應(yīng)性
Human

克隆號(hào)
2B7C12

亞型
IgG1

通用名
SIGLEC3

基因ID

UniProt ID

功能
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, E

稀釋方法
WB~~1/500 - 1/2000 FC~~1:200~~400 ICC~~1:200~~1000 IF~~1:200~1000.

圖像

Figure 1: Western blot analysis using CD33 mouse mAb against truncated Trx-CD33 recombinant protein (1),truncated CD33 (aa48-258)-His recombinant protein (2) and truncated CD33 (aa18-259)-hIgGFc transfected CHO-K1 cell lysate (3).

Figure 3: Flow cytometric analysis of MCF-7 cells using beta Actin mouse mAb (right) and negative control (left).

Figure 2: Confocal immunofluorescence analysis of SKBR-3 (left) and A549 (right) cells using beta Actin mouse mAb (red, the secondary Ab is Cy3-Goat anti mouse IgG). Blue: DRAQ5 fluorescent DNA dye.

說明書

數(shù)量

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