品牌 |
Leading Biology |
貨號(hào) |
AMM02316G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FGF19 Antibody (clone FG98-6).
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分子量 |
24003 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.
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克隆號(hào) |
FG98-6
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亞型 |
IgG2b,k
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基因ID |
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UniProt ID |
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功能 |
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
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總結(jié) |
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:500 - 1:1000), IHC-P (15 μg/ml), WB (1:500 - 1:1000),
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圖像 |
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis using anti-FGF-19 (human), mAb (FG98-6) at 1:2000 dilution.
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說(shuō)明書(shū) |
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數(shù)量 |
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