品牌 |
Leading Biology |
貨號 |
AMM02809G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOX2 Antibody.
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分子量 |
34kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:17097055}
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
10F10
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亞型 |
IgG1
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通用名 |
Sox-2
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, ICC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
IHC~~1/500 - 1/2000
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圖像 |
Figure 1: Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2(AA: 2-317)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.
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說明書 |
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數(shù)量 |
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