品牌 |
Leading Biology | 貨號 |
AMM03740G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LIMK2 Antibody (monoclonal) (M01).
|
||
分子量 |
72232 Da
|
||
宿主 |
mouse
|
||
種屬反應(yīng)性 |
Human
|
||
靶點 |
LIMK2 (AAH13051.1, 1 a.a. ~ 686 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
|
||
克隆號 |
2H2-E11
|
||
亞型 |
IgG1 Kappa
|
||
基因ID |
|||
UniProt ID |
|||
總結(jié) |
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.
|
||
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應(yīng)用 |
WB, IF, E
|
||
稀釋方法 |
WB~~1:500~1000
|
||
圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (101.0899 KDa) . Western Blot analysis of LIMK2 expression in transfected 293T cell line by LIMK2 monoclonal antibody (M01), clone 2H2-E11.Lane 1: LIMK2 transfected lysate(72.232 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of monoclonal antibody to LIMK2 on HeLa cell . [antibody concentration 10 ug/ml] |
||
說明書 |
|||
數(shù)量 |
|
選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
1 | Leading Biology | APG01369G | VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide | 100 μg | Monoclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
2 | Leading Biology | AMM07627G | RIN2 Antibody (monoclonal) (M01) | 100 μg | Monoclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
3 | Leading Biology | APR15980G | FGG Antibody | 100 μl | Monoclonal Antibodies |
|
¥5450.00 | 訂購 詢價 | ||
4 | Leading Biology | AMM05161G | GOB5 / CLCA1 Antibody (clone 1C4) | 50 μg | Monoclonal Antibodies |
|
¥5450.00 | 訂購 詢價 | ||
5 | Leading Biology | APR17667G | ORAI1 Antibody [3F6H5] | 0.1 mg | Monoclonal Antibodies |
|
¥6950.00 | 訂購 詢價 | ||
6 | Leading Biology | APR11118G | HIV-1 p24 Antibody [7F4] (biotin) | 0.1 mg | Monoclonal Antibodies |
|
¥6950.00 | 訂購 詢價 |
微信掃描二維碼,隨時隨地與小諾親密接觸,精彩活動,勁爆優(yōu)惠,觸手可得!