Glycophorin A / CD235a (Erythrocyte Marker) Antibody

AMM00812G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM00812G		7 ml / ￥4950

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安諾倫（北京）生物科技有限公司

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Glycophorin A / CD235a (Erythrocyte Marker) Antibody

品牌	Leading Biology	貨號(hào)	AMM00812G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Glycophorin A / CD235a (Erythrocyte Marker) Antibody.
分子量	39kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	GYPA/280
亞型	Mouse / IgG1, kappa
通用名	GPA
基因ID	2993
UniProt ID	P02724
功能	Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).
總結(jié)	Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, IF, FC
圖像	Formalin-fixed, paraffin-embedded human Placenta stained with Glycophorin A Monoclonal Antibody (GYPA/280) Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Glycophorin A Monoclonal Antibody (GYPA/280)
說(shuō)明書	Product Datasheet Protocol
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Glycophorin A / CD235a (Erythrocyte Marker) Antibody