全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM02566G |
產品分類 |
Monoclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB21 Antibody.
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分子量 |
24348 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus, trans- Golgi network. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane Cleavage furrow. Note=Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid- telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells. {ECO:0000250|UniProtKB:P35282, ECO:0000250|UniProtKB:Q6AXT5}
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宿主 |
Mouse
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種屬反應性 |
Human, African Green Monkey
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靶點 |
This RAB21 antibody is generated from a mouse immunized with a recombinant protein between 1-225 amino acids from the human RAB21.
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克隆號 |
1701CT536.68.39
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亞型 |
IgG2b,κ
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通用名 |
KIAA0118
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基因ID |
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UniProt ID |
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功能 |
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
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總結 |
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:2000
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圖像 |
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說明書 |
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數量 |
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