品牌 |
Leading Biology | 貨號(hào) |
AMM02325G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P100 Antibody.
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分子量 |
85653 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
Multiple aa
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靶點(diǎn) |
This monoclonal antibody is generated from mice immunized with a collection of antigenic peptides from different regions of P100.
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克隆號(hào) |
19AT953.286.93
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亞型 |
Mouse IgG1
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通用名 |
C20orf1, C20orf2, DIL2, HCA519
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基因ID |
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UniProt ID |
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功能 |
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:100~500
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圖像 |
Western blot analysis of lysates from HT29, Jurkat, MCF-7 cell line (from left to right), using P100 Antibody(19AT953. 286. 93). 19AT953. 286. 93 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane. Western analysis of extracts from Jurkat cells using P100 antibody. |
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說明書 |
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數(shù)量 |
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