全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM02427G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CST3 Antibody.
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分子量 |
15799 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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免疫原 |
95-122 aa
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靶點 |
This CST3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from human CST3.
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克隆號 |
572CT4.3.2
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
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總結(jié) |
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatinproteins are a class of cysteine proteinase inhibitors found in avariety of human fluids and secretions, where they appear toprovide protective functions. The cystatin locus on chromosome 20contains the majority of the type 2 cystatin genes and pseudogenes.This gene is located in the cystatin locus and encodes the mostabundant extracellular inhibitor of cysteine proteases, which isfound in high concentrations in biological fluids and is expressedin virtually all organs of the body. A mutation in this gene hasbeen associated with amyloid angiopathy. Expression of this proteinin vascular wall smooth muscle cells is severely reduced in bothatherosclerotic and aneurysmal aortic lesions, establishing itsrole in vascular disease.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:100~800
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圖像 |
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說明書 |
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數(shù)量 |
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