CDKN1C Antibody (Ascites)

AMM02415G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM02415G		0.1 ml / ￥4950

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CDKN1C Antibody (Ascites)

品牌	Leading Biology	貨號(hào)	AMM02415G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN1C Antibody (Ascites).
分子量	32177 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	34-64 aa
靶點(diǎn)	This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.
克隆號(hào)	522CT9.5.1
亞型	IgM
通用名	KIP2
基因ID	1028
UniProt ID	P49918
功能	Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.
總結(jié)	This gene is imprinted, with preferential expression ofthe maternal allele. The encoded protein is a tight-binding, stronginhibitor of several G1 cyclin/Cdk complexes and a negativeregulator of cell proliferation. Mutations in this gene areimplicated in sporadic cancers and Beckwith-Wiedemann syndorome,suggesting that this gene is a tumor suppressor candidate. Threetranscript variants encoding two different isoforms have been foundfor this gene.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:500~16000
圖像	CDKN1C Antibody (Cat. AMM02415G) western blot analysis in HL-60 cell line lysates (35μg/lane).This demonstrates the CDKN1C antibody detected the CDKN1C protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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