品牌 |
Leading Biology | 貨號 |
AMM02362G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VIME Antibody.
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分子量 |
53652 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
This VIME monoclonal antibody is generated from mouse immunized with VIME recombinant protein.
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克隆號 |
280CT3.4.6
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亞型 |
IgM,k
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基因ID |
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UniProt ID |
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功能 |
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
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總結(jié) |
This gene encodes a member of the intermediate filamentfamily. Intermediate filamentents, along with microtubules andactin microfilaments, make up the cytoskeleton. The protein encodedby this gene is responsible for maintaining cell shape, integrityof the cytoplasm, and stabilizing cytoskeletal interactions. It isalso involved in the immune response, and controls the transport oflow-density lipoprotein (LDL)-derived cholesterol from a lysosometo the site of esterification. It functions as an organizer of anumber of critical proteins involved in attachment, migration, andcell signaling. Mutations in this gene causes a dominant,pulverulent cataract.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:100~250
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圖像 |
VIME Antibody (Cat. AMM02362G) western blot analysis in Hela cell line lysates (35μg/lane).This demonstrates the VIME antibody detected the VIME protein (arrow). |
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說明書 |
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數(shù)量 |
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