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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Eosinophil Peroxidase (EPX) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
AMM00060G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Eosinophil Peroxidase (EPX) Antibody - With BSA and Azide.
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分子量 |
70kDa (55kDa-Heavy Chain; 15kDa-Light Chain)
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human eosinophils from a patient with hypereosinophilic syndrome
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克隆號(hào) |
AHE-1
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亞型 |
IgG1, kappa
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通用名 |
EPER, EPO, EPP
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基因ID |
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UniProt ID |
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功能 |
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
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總結(jié) |
Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC, E
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說明書 |
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數(shù)量 |
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