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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > HIV-1 p24 Antibody [7F4] (biotin)

HIV-1 p24 Antibody [7F4] (biotin)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR11118G 0.1 mg / ¥6950

HIV-1 p24 Antibody [7F4] (biotin)

品牌

Leading Biology

貨號(hào)

APR11118G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HIV-1 p24 antibody [7F4] (biotin).

分子量

Predicted: 24, 41, 55 kDa

細(xì)胞定位

Antigen Cellular Localization: Matrix protein p17: Virion. Host nucleus. Host cytoplasm. Host cell membrane; Lipid-anchor Note=Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity). Nucleocapsid protein p7: Virion

宿主

Mouse

種屬反應(yīng)性

Virus

靶點(diǎn)

GAG; By Western blot, anti-HIV-1 p24 antibody detects a ~24 kDa, a ~41 kDa, and a ~55 kDa protein, corresponding to HIV-1 p24 and to its precursors p41 and p55, respectively, in HIV-1 samples.

克隆號(hào)

7F4

亞型

IgG1

基因ID

UniProt ID

功能

Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers.

總結(jié)

HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

圖像

Western blot analysis of 20 ng of HIV-1 p24 protein with PM-6585-biotin at 0.2 μg/mL.

說(shuō)明書(shū)

數(shù)量

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