品牌 |
Leading Biology |
貨號 |
AMM04437G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ERP44 antibody (clone 3C7).
|
分子量 |
47kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen.
|
宿主 |
Mouse
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種屬反應(yīng)性 |
Human
|
靶點 |
Human TXNDC4
|
克隆號 |
3C7
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通用名 |
KIAA0573, TXNDC4
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基因ID |
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UniProt ID |
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功能 |
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
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總結(jié) |
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
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形式 |
Liquid
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E, IP
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稀釋方法 |
IHC-P (3-5 μg/ml), WB (1:500-1:1000),
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別名 |
Endoplasmic reticulum resident protein 44, ER protein 44, ERp44, Thioredoxin domain-containing protein 4, ERP44, KIAA0573, TXNDC4
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圖像 |
Antibody AMM04437G, Western blot of TXNDC4 expression in A-431.
Antibody AMM04437G Western blot of TXNDC4 expression in K-562.
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說明書 |
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數(shù)量 |
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