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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > ARNT / HIF-1-Beta Antibody (clone 3D10)

ARNT / HIF-1-Beta Antibody (clone 3D10)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG01990G 50 μg / ¥5450

ARNT / HIF-1-Beta Antibody (clone 3D10)

品牌

Leading Biology

貨號

APG01990G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARNT / HIF-1-Beta antibody (clone 3D10).

分子量

87kDa

細(xì)胞定位

Antigen Cellular Localization: Nucleus.

宿主

Mouse

種屬反應(yīng)性

Human

靶點(diǎn)

Human ARNT

克隆號

3D10

通用名

BHLHE2

基因ID

UniProt ID

功能

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

總結(jié)

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

稀釋方法

IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)

別名

Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Class E basic helix-loop-helix protein 2, bHLHe2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta, ARNT, BHLHE2

圖像

Western blot of ARNT expression in HeLa nuclear extract.

Western blot of ARNT expression in transfected 293T cell line.

Immunofluorescence of monoclonal antibody to ARNT on HeLa cell. [antibody concentration 10 ug/ml]

說明書

數(shù)量

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