品牌 |
Leading Biology | 貨號 |
APC00051G |
產品分類 |
Monoclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GAX / MEOX2 antibody (clone 6A5).
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分子量 |
34kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
Human Homeobox Protein Mox-2
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克隆號 |
6A5
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通用名 |
GAX, MOX2
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基因ID |
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UniProt ID |
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功能 |
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
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總結 |
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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稀釋方法 |
IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)
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別名 |
Homeobox protein MOX-2, Growth arrest-specific homeobox, Mesenchyme homeobox 2, MEOX2, GAX, MOX2
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圖像 |
MEOX2 monoclonal antibody clone 6A5 Western blot of MEOX2 expression in HeLa. MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in PC-12. MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in NIH/3T3. |
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說明書 |
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數(shù)量 |
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