全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06349G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MECP2 antibody (clone 4B6).
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分子量 |
52kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Colocalized with methyl-CpG in the genome
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
Human MeCP2
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克隆號 |
4B6
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基因ID |
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UniProt ID |
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功能 |
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).
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總結(jié) |
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (5 μg/ml), WB (1:500-1:1000),
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別名 |
Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2
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圖像 |
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說明書 |
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數(shù)量 |
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