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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > AKR1C4 / Chlordecone Reductase Antibody (clone 2C11)品牌 |
Leading Biology | 貨號 |
APG01664G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AKR1C4 / Chlordecone Reductase antibody (clone 2C11).
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分子量 |
37kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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種屬反應性 |
Human
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靶點 |
Human AKR1C4
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克隆號 |
2C11
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通用名 |
CHDR
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
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總結(jié) |
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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稀釋方法 |
IF (15 μg/ml), IHC-P (5 μg/ml),
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別名 |
Aldo-keto reductase family 1 member C4, 1.1.1.-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, 1.1.1.357, Chlordecone reductase, CDR, 1.1.1.225, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
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圖像 |
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說明書 |
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數(shù)量 |
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