品牌 |
Leading Biology | 貨號(hào) |
APR17884G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TWIST2 antibody (clone 3C8).
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分子量 |
18kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11062344}. Cytoplasm. Note=Mainly nuclear during embryonic development. Cytoplasmic in adult tissues
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
3C8
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通用名 |
BHLHA39, DERMO1
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基因ID |
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UniProt ID |
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功能 |
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
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總結(jié) |
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (5 μg/ml)
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別名 |
Twist-related protein 2, Class A basic helix-loop-helix protein 39, bHLHa39, Dermis-expressed protein 1, Dermo-1, TWIST2, BHLHA39, DERMO1
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圖像 |
Western blot of TWIST2 expression in transfected 293T cell line by TWIST2 monoclonal antibody,... Anti-TWIST2 antibody IHC of human kidney. Anti-TWIST2 antibody IHC of human testis. |
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說(shuō)明書(shū) |
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數(shù)量 |
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