全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM07004G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EDEM2 antibody (clone 2E4).
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分子量 |
65kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Endoplasmic reticulum lumen.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
2.00E+04
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通用名 |
C20orf31, C20orf49
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基因ID |
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UniProt ID |
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功能 |
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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總結(jié) |
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (2.5 μg/ml)
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別名 |
ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31, C20orf49
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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