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GOK / STIM1 Antibody (clone 5A2)

AMM05164G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM05164G		50 μg / ￥5450

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GOK / STIM1 Antibody (clone 5A2)

品牌	Leading Biology	貨號	AMM05164G
產(chǎn)品分類	Monoclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GOK / STIM1 antibody (clone 5A2).
分子量	77kDa
細胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane. Associated with the microtubule network at the growing distal tip of microtubules
宿主	Mouse
種屬反應性	Human
克隆號	5A2
通用名	GOK
基因ID	6786
UniProt ID	Q13586
功能	Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
總結	Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, IF, E
稀釋方法	IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)
別名	Stromal interaction molecule 1, STIM1, GOK
圖像	STIM1 monoclonal antibody clone 5A2. Western blot of STIM1 expression in human liver. Immunofluorescence of monoclonal antibody to STIM1 on HeLa cell (antibody concentration 10 ug/ml). Anti-STIM1 antibody IHC of human small intestine, submucosal plexus.
說明書	Product Datasheet Protocol
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