品牌 |
Leading Biology | 貨號 |
AMM05385G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HNRNP-E2 / PCBP2 antibody (clone 5F12).
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分子量 |
39kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
5F12
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基因ID |
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UniProt ID |
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功能 |
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
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總結(jié) |
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E, RNAi
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稀釋方法 |
IF (10 μg/ml), IHC-P (5 μg/ml),
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別名 |
Poly(rC)-binding protein 2, Alpha-CP2, Heterogeneous nuclear ribonucleoprotein E2, hnRNP E2, PCBP2
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圖像 |
Western blot of PCBP2 expression in transfected 293T cell line by PCBP2 monoclonal antibody... PCBP2 monoclonal antibody clone 5F12 Western blot of PCBP2 expression in K-562. Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell (antibody concentration 10 ug/ml). |
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說明書 |
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數(shù)量 |
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