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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > SFN / Stratifin / 14-3-3 Sigma Antibody (clone 3C3)

SFN / Stratifin / 14-3-3 Sigma Antibody (clone 3C3)

貨號 貨期 規(guī)格 / 價格 詢價
APR13297G 50 μg / ¥5450

SFN / Stratifin / 14-3-3 Sigma Antibody (clone 3C3)

品牌

Leading Biology

貨號

APR13297G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFN / Stratifin / 14-3-3 Sigma antibody (clone 3C3).

分子量

28kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway

宿主

Mouse

種屬反應(yīng)性

Human

克隆號

3C3

通用名

HME1

基因ID

UniProt ID

功能

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

總結(jié)

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P

稀釋方法

IHC-P (5 μg/ml)

別名

14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1

圖像

SFN monoclonal antibody, clone 3C3 Western blot of SFN expression in HeLa.

Anti-SFN / 14-3-3 Sigma antibody IHC of human skin.

Anti-SFN / 14-3-3 Sigma antibody IHC of human thymus.

說明書

數(shù)量

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