品牌 |
Leading Biology |
貨號 |
APR10367G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Syntaxin 1A antibody.
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分子量 |
36 KDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Hamster, Pig, Rat
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靶點 |
Synaptic immunoprecipitate (crude) from human brain.
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克隆號 |
SP8
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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總結(jié) |
Syntaxins are a family of proteinsinvolved in the docking of synapticvesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, formsthe SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding ofMunc18-1 to the N-terminus of syntaxin 1 hasbeen demonstrated to be essential for exocyticmembrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 inthe prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).
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形式 |
Protein G purified culture supernatant.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:1000
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別名 |
Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
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圖像 |
Western blot of rat cortex lysate showing specific immunolabelingof the ~ 36k syntaxin 1A protein.
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說明書 |
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數(shù)量 |
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