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Calcitonin Gene Related Peptide (CGRP) Antibody品牌 |
Leading Biology | 貨號 |
APR11543G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Calcitonin Gene Related Peptide (CGRP) antibody.
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分子量 |
13948 Da
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Rat
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靶點 |
Purified rat alpha-CGRP.
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克隆號 |
4901
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亞型 |
IgG2a
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基因ID |
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UniProt ID |
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總結(jié) |
Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993)
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形式 |
Protein G purified
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
ICC
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稀釋方法 |
ICC~~1:50-1:100
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別名 |
Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca, Calc
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圖像 |
Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. Cells were obtained and photo was provided courtesy of QBMCellScience. |
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說明書 |
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數(shù)量 |
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